Drospirenone

Drospirenone is a synthetic progestin that is an analog to spironolactone. A progestin is a synthetic progestogen that has some biological activity similar to progesterone.
The two most frequent uses of progestins, such as Drosperinone, are for hormonal contraception (either alone or with an estrogen), and to prevent endometrial hyperplasia from unopposed estrogen in hormone replacement therapy.

Drospirenone  is part of certain birth control formulations. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic.

Drospirenone is part of certain newer oral contraceptive formulations:

• Yasmin contains 3 mg drospirenone and 30 mcg ethinylestradiol per tablet.
• Yasminelle contains 3 mg drospirenone and 20 mcg ethinylestradiol per tablet
• Yaz contains 3 mg drospirenone and 20 mcg ethinylestradiol per tablet

Drospirenone has also been formulated in medication to manage menopausal symptoms using 0.5 mg Drospirenone and 1 mg estradiol per day by oral application. This medication was introduced in the USA in 2007 as Angeliq

General data on Drospirenone Active Pharmaceutical Ingredient

Molecular Weight of Drosperinone :366.5
Drospirenone CAS Registry: 67392-87-4
Drospirenone ATC code: G03AA12

TAPI's Drosperinone Pharmaceutical Ingredient

TAPI's Drospirenone active pharmaceutical ingredient is produced in Corticosteroidi s.r.l. Santhia site – TAPI's highly potency APIs site in Italy.

Drospirenone is highly potent active pharmaceutical ingredients, belongs to the hormone contraceptive and replacement therapy group of drugs. These drugs are highly potent active pharmaceutical ingredients that need special handle in production or preparation. As highly potent drug, Drosperinone is considered to be small volume Active Pharmaceutical Ingredient.

TAPI provides full service on Droepirenone and other APIs in our portfolio. We provide information on TAPI's Drospirenone, the regulatory compliance with various health regulations and documentation. Contact us today for further inquiries and samples and kilograms availability information for TAPI's Drospirenone.

TAPI is a world leading developer and manufacturer of highly potent drugs used by innovative and generic companies to formulate their final dosage medications. TAPI highly potent manufacturing plants are located mainly in Italy (Sicor S.r.l. ) and Mexico ( Sicor de Mexico) . TAPI highly potent active pharmaceutical ingredients, such as Drospirenone, are used in oral, parenteral, topical and inhalation therapies; and most fall in four classes: Steroids, Oncolytics, Hormones, Non-depolarizing muscle relaxants, Immunosuppressants. Amongst those can be  found product such as as Alclometasone, Amcinonide, Beclometasone, Betamethasone, Budesonide, Clobetasone, Clobetasol Propionate, Deflazacort , Dexamethasone, Fluocinolone acetonide, Fluocinonide, Fluticasone, Methylprednisolone, Mometasone furoate, Prednicarbate, Prednisone, Triamcinolone.

Contact us today for information on TAPI's Droepirenone and other highly potent Active Pharmaceutical Ingredients.

Legal Note

Product exploitation, including development, sales and offer for sale are performed where permissible by patent law. This presentation is not and should not constitute an offer for sale in territories where it is not permitted by law. In USA Products  that  Currently on Patent are available for R&D Use in Accordance with 35 USC §271 (e) (1).

*TAPI stands for Teva's Active Pharmaceutical Ingredients