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PLIVA Hrvatska d.o.o

Savski Marof

Savski Marof

Site at a Glance:

Established: 1878
Acquired by PLIVA: 1967
Acquired by TAPI: 2008
Plant Size: 390,000 m²
Total Reactor Volume: 243 m³

The TAPI Croatia - PLIVA Savski Marof production plant is located in Savski Marof, a village near the town of Zaprešić.
The site comprises two multipurpose production units:

Synthesis SM1, with a total reactor volume of 108 m³ Multipurpose Synthesis Plant (MPS), with a total reactor volume 135 m³, and offering ancillary services such as warehouse storage and utility production

The site supports a large variety of chemical reactions performed at temperatures ranging from -20 to 140 o C and pressures up to 20 bar.


The Savski Marof plant serves as a center of excellence for hydrogenation within TAPI, and the MPS is one of the top state-of-the-art API plants worldwide. A new Miniplant unit has been built for new product transfers and small-scale API production.
The site is regularly audited by leading regulatory agencies (including the FDA, EMA/MHRA, and HALMED) and TAPI’s business partners.
Savski Marof Site
Prudnička cesta 98
10291 Prigorje Brdovečko